Research Library

Artigos técnicos, revisões sobre mecanismos e guias de pesquisa, organizados por sistema biológico. Sem conclusões que extrapolem as evidências.
A Molécula do Tempo – O Composto que Seu Corpo Produz e Para de Produzir Gradualmente
Regenerative System
The Molecule of Time – The Compound Your Body Makes and Gradually Stops Making

Somewhere between your twenties and your sixties, your body quietly reduces its production of a molecule that science believes sits at the center of your capacity to regenerate. This molecule has three amino acids. And almost no one knows its name.

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The Copper That Builds – An Ancient Mineral and Three Amino Acids in Tissue Regeneration Research
Regenerative System
The Copper That Builds – An Ancient Mineral and Three Amino Acids in Tissue Regeneration Research

The Copper That Builds, how an ancient mineral and three amino acids became an object of research in tissue regeneration

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The Sleeping Cells – IGF-1 LR3 and the Biology of Muscle Satellite Cells
GH Axis System
The Sleeping Cells – IGF-1 LR3 and the Biology of Muscle Satellite Cells

The Sleeping Cells That May Change What We Understand About Muscle Growth

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The Surprised Genome – When a Three-Amino-Acid Molecule Met the Human Genome
Regenerative System
The Surprised Genome – When a Three-Amino-Acid Molecule Met the Human Genome

The Surprised Genome, when MIT researchers pointed a three-amino acid molecule at the human genome, the result surprised everyone, including them

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The Guardians of the Genome – NAD+ and the Seven Sirtuins
Mitochondrial Energy System
The Guardians of the Genome – NAD+ and the Seven Sirtuins

The Guardians of the Genome Need Permission to Act, and NAD+ Is the Key

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The Molecule That Reached the Heart – SS-31 and Mitochondrial Cardiology
Mitochondrial Energy System
The Molecule That Reached the Heart – SS-31 and Mitochondrial Cardiology

How a synthetic tetrapeptide traveled through decades of science and reached Phase III clinical trials for one of the most difficult heart conditions to treat, and what that reveals about the future of mitochondrial research.

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The Knowledge That Stayed Behind the Curtain – The History of Semax
Neural & Cognitive System
The Knowledge That Stayed Behind the Curtain – The History of Semax

It was the late 1970s. The Cold War was at its peak. While the two superpowers competed for space and for nuclear arsenals, a group of scientists at the Russian Academy of Sciences worked on an apparently very different problem: how to enhance the cognitive function of military pilots and cosmonauts under extreme stress conditions.

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The Protein Your Brain Uses to Learn – Semax and the BDNF/TrkB Axis
Neural & Cognitive System
The Protein Your Brain Uses to Learn – Semax and the BDNF/TrkB Axis

There is a protein in your brain that decides what you will remember. It is not a neurotransmitter. It is not a hormone. It is a protein called BDNF, Brain-Derived Neurotrophic Factor. And over the past twenty years, it has become one of the objects of desire of modern neuroscience.

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The Cascade That Controls Cell Growth – IGF-1 LR3 and PI3K/Akt/mTOR
GH Axis System
The Cascade That Controls Cell Growth – IGF-1 LR3 and PI3K/Akt/mTOR

At the heart of cell-growth biology there is a sequence of proteins that activate in a chain. Understanding that cascade, and how to manipulate it experimentally, is one of the most active frontiers of modern biochemistry.

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Why Research Chose the Fragment – TB-500 and the Future of Molecular Biology
Regenerative System
Why Research Chose the Fragment – TB-500 and the Future of Molecular Biology

Regenerative System • TB-500 • Translational Research • Fragment Biology

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The Peptide Your Body Makes When You Move
Mitochondrial Energy System
The Peptide Your Body Makes When You Move

Scientists discovered that physical exercise triggers the production of a molecule called MOTS-c directly within the mitochondria. Now, researchers are investigating what happens when that signal is amplified, or when it fades with age.

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Hacking the Hormone – How CJC-1295 Was Engineered Amino Acid by Amino Acid
GH Axis System
Hacking the Hormone – How CJC-1295 Was Engineered Amino Acid by Amino Acid

How scientists redesigned one of the body’s own molecules, four letters at a time, to create one of the most studied tools in longevity research.

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